Bojesodok-eum, a Herbal Prescription, Ameliorates Acute Inflammation in Association with the Inhibition of NF-B-Mediated Nitric Oxide and ProInflammatory Cytokine Production
Figure 5
Inhibition of LPS-inducible iNOS and COX-2 by BSE. (a) iNOS and COX-2, immunoblottings (upper). iNOS, COX-2, or COX-1 protein levels were monitored 12 h after treatment with LPS (1 μg/mL). Relative iNOS and COX-2 protein levels of the upper immunoblottings (lower). Values represent the mean S.E.M. (significantly different as compared to LPS-treated group, *, *). (b) Inhibition of LPS-inducible COX activity by BSE. The COX, COX-1, or COX-2 enzyme activity was measured as described in the Methods section. Data represents the mean ± S.E.M. from three separate experiments (significant as compared with LPS alone, ##). BSE: Bojesodok-eum.
