Research Article

Impact of Global Normalization in fMRI Acupuncture Studies

Table 3

Changes of activations between PSGS and NO PSGS.

RegionsTactileAcupuncture
Increased voxels no.Decreased voxels no.Disappeared voxels no.Arisen voxels no.Increased voxels no.Decreased voxels no.Disappeared voxels no.Arisen voxels no.

Brainstem
 MidbrainL44644614256
R1156152123

Inferior frontal gyrus(9)
 BA 9, 44, 45, 46, 47L29 (31)72 (94)23 (19)10 (14)15 (16)
R48 (61)134 (208)38 (57)8 (12)13 (22)(16)
Medial frontal gyrus
 BA 6, 8, 32L58 (5)711 (11)
R16 (11)29 (5)55
Middle frontal gyrus
 BA 6, 8, 9L512 (5)47 (35)
R18 (25)77 (120)22 (17)
Superior frontal gyrus
 BA 6, 8L713 (5)6
R20 (7)17 (35)1667 (16)6
Precentral gyrus
 BA 4, 6, 43, 44L650 (49)34 (23)26 (30)9 (22)11 (6)
R539 (42)37 (30)34 (36)6 (12)(6)

Anterior cingulate
 BA 24, 33L185(6)
R55 (5)
Cingulate gyrus
 BA 24, 32L(12)22 (46)55 (16)21 (17)9 (33)9 (8)
R40 (36)11 (6)22 (17)16 (5)

Postcentral gyrus
 BA 1, 2, 3L65122202613
R9291929
 BA 40, 43L29 (106)14 (47)26 (59)(60)12 (38)
R(20)25 (78)10 (29)23 (91)(5)
Inferior parietal lobule
 BA 40L11 (12)89 (107)77 (78)80 (42)16 (48)20 (26)
R551 (74)33 (40)31 (62)53 (40)12 (26)
Supramarginal gyrus
 BA 40L5 (8)9 (41)5
R5 (20)58 (5)(12)
 ThalamusL6392455327
R2944423325
Insula
 BA 13L5 (25)108 (108)96 (102)107 (91)24 (31)20 (28)(5)
R6 (18)71 (165)89 (110)43 (170)17 (21)12 (12)6 (14)
 ClaustrumL31213551212
R133179
Extranuclear
 BA 13L(7)(124)(200)(38)5 (27)(93)(21)
R(10)(37)(308)(133)(16)(48)(21)
 CaudateR13
 PutamenL801018851732
R211451051520
 Lateral globus pallidusL17
R5
Subgyral
 BA 21L(16)9 (71)(130)6 (17)(14) (50)(10)
R(11)6 (46)(109)5 (75)(7)

Parahippocampal gyrus
 BA 34L5 (13)
R5 (7)
 AmygdalaL5
R5
Fusiform gyrus
 BA 19R9 (11)
Middle temporal gyrus
 BA 21, 37, 39L(10)21 (58)(15)(12)6 (10)
R(8)8 (27)38 (57)(25)(20)(21)
Superior temporal gyrus
 BA 22, 38, 41, 42L(5)92 (97)98 (133)89 (20)25 (13)28 (21)19 (9)
R20 (13)50 (63)92 (67)43 (138)8 (5)12 (7)10 (11)
Transverse temporal gyrus
 BA 41, 42L20 (7)21 (4)
R1057 (10)

Cerebellum
 DentateL819
 CulmenL5292032
R13324
 DecliveL1971114120707410
R627117135137
 Cerebellar tonsilL516
R5
 FastigiumL7
 NoduleL8
 Inferior semilunar lobuleL4132
R35
 PyramisL11752055
R27

 TuberL83730
 UvulaL29431534
R27

The coordination of voxel with the maximal t within each region is listed. The regions are thresholded at , uncorrected. The number of detected white matter is listed in the parenthesis of each region.
Abbreviations: BA: Brodmann area; L: left; R: right.