Hesperetin, a Selective Phosphodiesterase 4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness without Influencing Xylazine/Ketamine-Induced Anesthesia
Figure 5
Effects of subcutaneously administered Ro 20-1724 (a) and hesperetin (b) on the duration of xylazine (10 mg/kg, i.p.)/ketamine-induced (70 mg/kg, i.p.) anesthesia in mice. Ro 20-1724 was administered 0.25 h and hesperetin 1 h before anesthesia. **, compared to the vehicle (control). Each value represents the mean . The number of mice in each group was 10.
