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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 480715, 9 pages
http://dx.doi.org/10.1155/2012/480715
Research Article

Traditional Chinese Medicine ZHENG Identification Provides a Novel Stratification Approach in Patients with Allergic Rhinitis

1Department of Otolaryngology, Taichung Veterans General Hospital, Taichung 40705, Taiwan
2School of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan
3Department of Endocrinology and Metabolism, Taichung Veterans General Hospital, Taichung 40705, Taiwan
4Department of Traditional Chinese Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan
5Graduate Institute of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 40421, Taiwan

Received 13 January 2012; Revised 4 April 2012; Accepted 6 April 2012

Academic Editor: Shi-Bing Su

Copyright © 2012 Kai-Li Liang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. We aimed to apply the ZHENG identification to provide an easy and useful tool to stratify the patients with allergic rhinitis (AR) through exploring the correlation between the quantified scores of AR symptoms and the TCM ZHENGs. Methods. A total of 114 AR patients were enrolled in this observational study. All participants received the examinations of anterior rhinoscopy and acoustic rhinometry. Their blood samples were collected for measurement of total serum immunoglobulin E (IgE), blood eosinophil count (Eos), and serum eosinophil cationic protein (ECP). They also received two questionnaire to assess the severity scores of AR symptoms and quantified TCM ZHENG scores. Multiple linear regression analysis was used to determine explanatory factors for the score of AR manifestations. Results. IgE and ECP level, duration of AR, the 2 derived TCMZHENG scores of “Yin-Xu − Yang-Xu”, and “Qi-Xu + Blood-Xu” were 5 explanatory variables to predict the severity scores of AR symptoms. The patients who had higher scores of “Yin-Xu − Yang-Xu” or “Qi-Xu + Blood-Xu” tended to manifest as “sneezer and runner” or “blockers,” respectively. Conclusions. The TCM ZHENG scores correlated with the severity scores of AR symptoms and provided an easy and useful tool to stratify the AR patients.