Dual Roles of Quercetin in Platelets: Phosphoinositide-3-Kinase and MAP Kinases Inhibition, and cAMP-Dependent Vasodilator-Stimulated Phosphoprotein Stimulation
Quercetin attenuates fibrinogen binding to integrin . Fibrinogen binding to integrin in platelets pre-treated with quercetin and stimulated by collagen (2.5 μg/mL) together with Alexa Fluor 488-human fibrinogen (200 μg mL−1) followed by incubation at 37°C for 15 min. (a) Tracings are representatives of 4 independent experiments. (b) Bar graph represents summary of quercetin effects on fibrinogen binding. *, **.