Effect of Mucuna pruriens Seed Extract Pretreatment on the Responses of Spontaneously Beating Rat Atria and Aortic Ring to Naja sputatrix (Javan Spitting Cobra) Venom

Table 1

Effects of Naja sputatrix venom on the contraction of aortic rings isolated from MPE-pretreated and untreated rats.

Venom concentration (μg/mL)	Aortic ring contraction
	(% phenylephrine contraction)
	Untreated	MPE-pretreated
5	3.5 ± 1.6	5.3 ± 2.0
50	16.5 ± 2.9^##	14.6 ± 2.7^#
250	112.5 ± 14.9^###	115.7 ± 15.4^###

Values represent mean ± S.E.M. (𝑛=9). The effect of concentration was analysed using one-way repeated measures ANOVA followed by Benferroni/Dunnett T3 post-hoc test. ^#𝑃<0.05, ^##𝑃<0.01, ^###𝑃<0.001 compared to 5 μg/mL. The difference in the means between the untreated and the MPE-pretreated groups was not significant at all three venom concentrations. 𝑃>0.05, unpaired Student’s t-test.