Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Fig 4

Research Article

Gallic Acid Enriched Fraction of Phyllanthus emblica Potentiates Indomethacin-Induced Gastric Ulcer Healing via e-NOS-Dependent Pathway

Figure 4

Effect of GAE on mucosal PGE2 synthesis in indomethacin-induced ulcerated mice. Ulceration in the mice was induced by indomethacin (18 mg/kg, single dose, p.o.). Treatment was carried out for 3 days with GAE (5 mg/kg, daily, p. o.) or omeprazole (3 mg/kg, p. o.) after ulcer induction. The mucosal PGE2 levels of the ulcerated untreated and treated mice were measured. The values are mean ± S.E. of four independent experiments, each with 8 mice/group. * 𝑃 < 0 . 0 0 1 , compared to normal mice; ** 𝑃 < 0 . 0 0 1 , compared to untreated mice.
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