Evidence-Based Complementary and Alternative Medicine

Research Article

Therapeutic Effects of Cortex acanthopanacis Aqueous Extract on Bone Metabolism of Ovariectomized Rats

Table 4

Effects of 12-week treatment with Cortex acanthopanacis extract (CAE) on serum level of osteocalcin (OC), interleukin-1 beta (IL-1 š›½ ), interleukin-6 (IL-6), parathyroid hormone (PTH), and calcitonin (CT) from rats.
Group š‘› OC (ng/mL)IL-1 š›½ (pg/mL)IL-6 (pg/mL)CT (ng/mL)PTH (pg/mL)
NC12 7 . 3 6 Ā± 1 . 9 4 2 4 3 . 3 5 Ā± 3 4 . 5 9 3 4 7 . 1 0 Ā± 6 6 . 5 0 9 . 8 8 Ā± 2 . 3 2 4 9 . 1 6 Ā± 1 2 . 9 5
Sham12 7 . 0 6 Ā± 1 . 7 4 2 3 8 . 6 2 Ā± 4 0 . 9 8 3 6 1 . 9 4 Ā± 7 0 . 2 0 1 1 . 2 6 Ā± 2 . 8 0 4 3 . 5 3 Ā± 1 3 . 3 1
OVX12 1 1 . 3 1 Ā± 2 . 4 1 a 3 1 6 . 2 7 Ā± 3 5 . 9 5 a 5 6 6 . 7 0 Ā± 8 1 . 5 4 a 6 . 1 3 Ā± 1 . 7 5 a 4 0 . 0 8 Ā± 1 3 . 1 4
E212 7 . 2 6 Ā± 2 . 0 2 c 2 3 1 . 8 9 Ā± 4 4 . 8 4 c 3 3 4 . 9 1 Ā± 7 7 . 2 8 c 1 2 . 1 4 Ā± 3 . 1 2 c 4 8 . 1 3 Ā± 1 0 . 9 4
FEE12 8 . 5 7 Ā± 1 . 9 2 c 2 4 8 . 5 9 Ā± 3 8 . 0 5 c 4 0 0 . 9 1 Ā± 5 7 . 9 7 c 9 . 2 6 Ā± 1 . 8 8 c 4 6 . 6 9 Ā± 9 . 5 1
CAE12 1 1 . 5 0 Ā± 2 . 8 4 2 7 9 . 0 7 Ā± 4 3 . 3 8 d 5 1 0 . 1 0 Ā± 6 6 . 0 1 7 . 9 0 Ā± 2 . 3 2 d 4 3 . 3 1 Ā± 1 2 . 8 0
Results are expressed as mean Ā± SD.
a š‘ƒ < 0 . 0 1 against Sham group (rats with Sham operation).
c š‘ƒ < 0 . 0 1 against OVX group (ovariectomized rats).
d š‘ƒ < 0 . 0 5 against OVX group.