Research Article

It Is Not Just Folklore: The Aqueous Extract of Mung Bean Coat Is Protective against Sepsis

Figure 4

Autophagy inhibitors impaired MBC-mediated reduction of cellular HMGB1 levels. Differentiated human macrophages were incubated with highly purified HMGB1 protein (2 mg/L) or LPS (0.4 mg/L) in the absence or presence of MBC extract (20 mg/L), Baf (100 nM), or 3-methyladenine (5.0 mM), respectively. Cellular HMGB1 levels were determined by Western blotting analysis. The results shown were representative of three independent experiments.