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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 503031, 7 pages
Research Article

Microbiological and Pharmacological Evaluation of the Micropropagated Rubus liebmannii Medicinal Plant

1Unidad de Investigación Médica en Farmacología, Hospital de Especialidades, CMNS XXI, Instituto Mexicano del Seguro Social (IMSS), Avenue Cuauhtémoc 330, Col. Doctores, 06720 Mexico City, DF, Mexico
2Centro de Investigación Biomédica del Sur (CIBIS), IMSS, Argentina No. 1, 62790 Xochitepec, MOR, Mexico
3Centro de Investigación Biomédica del Noreste (CIBIN), IMSS, San Luis Potosí y Dos de Abril, Col. Independencia, 64720 Monterrey, NL, Mexico
4Facultad de Medicina, Universidad Autónoma de Nuevo León (UANL), Avnue Fco. I. Madero y E. Aguirre Pequeño, Col. Mitras Centro, Monterrey, NL, Mexico
5Centro de Diagnóstico en Metabolismo Energético y Medicina Mitocondrial, Mexico City, DF, Mexico

Received 20 April 2012; Accepted 14 June 2012

Academic Editor: Wagner Vilegas

Copyright © 2012 Adelina Jiménez-Arellanes et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Rubus liebmannii is an endemic species from Mexico used in traditional medicine primarily to treat dysentery and cough. The in vitro activity against Giardia lamblia and Entamoeba histolytica that produces the ethanolic extract of the aerial parts of the plant led us to expand the pharmacological and phytochemical research of this species. Gastrointestinal disorders including amebiasis remain one of the health problems that need to be addressed and it is of interest to find alternatives that improve their treatment. Also, it is important to emphasize that R. liebmannii grows wild in the country and is not found in abundance; therefore, alternatives that avoid overexploitation of the natural resource are mandatory. Ongoing with the evaluation of the potentialities that R. liebmannii possesses for treating infectious gastrointestinal diseases, the aim of the present study was to evaluate the biological effects and the chemical composition of the micropropagated plant.