Cardioprotective Effects of 20(S)-Ginsenoside Rh2 against Doxorubicin-Induced Cardiotoxicity In Vitro and In Vivo

Table 1

Effects of doxorubicin and Rh2 on the parameters of ECG in tested rats (means ± SD, 𝑛=6).

Group	Control	Rh2; 20 mg/kg	DOX; 2 mg/kg	DOX plus Rh2; 5 mg/kg	DOX plus Rh2; 10 mg/kg	DOX plus Rh2; 20 mg/kg
Heart rate (times·min^−1)	426.2 ± 31.6	401.2 ± 38.9	472 ± 31.9	450.6 ± 59.1	408.2 ± 39.4*	411.4 ± 50.1
QRS complex (sec)	0.056 ± 0.005	0.052 ± 0.008	0.075 ± 0.006^#	0.06 ± 0.019	0.056 ± 0.011*	0.054 ± 0.005**

^#𝑃<0.01, compared with control group; *𝑃<0.05, compared with DOX group; **𝑃<0.01, compared with DOX group.
All data were expressed as means ± SD (𝑛=6).