Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Fig 6

Research Article

Analgesic and Antiinflammatory Activities of the Aqueous Extract from Plectranthus amboinicus (Lour.) Spreng. Both In Vitro and In Vivo

Figure 6

PA-inhibited LPS-induced proinflammatory cytokine and mediator productions. RAW 264.7 cells were pretreated with PA (0.1–0.5 mg/mL) for 30 min, and then stimulated with LPS (100 ng/mL). Culture media were collected at 24 h for (a) TNF-α and (b) nitrite analysis. (c) Cell viability in PA-treated cells was evaluated using the MTT assay. The results are displayed in percentage of control samples. Data are presented as mean ± SEM (n = 3) for three independent experiments; *P < 0.05, **P < 0.01, ***P < 0.001 as compared with the LPS treatment.

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