Curcumin-Induced Apoptosis in Human Hepatocellular Carcinoma J5 Cells: Critical Role of Ca⁺²-Dependent Pathway

Figure 5

Effects of pretreated BAPTA (Ca²⁺ chelator) for 2 h followed by the treatment of 25 μM curcumin in J5 cells on cell viability, ΔΨ_m, and ROS production. (a) cell viability, (b) ΔΨ_m, (c) ROS production, and (d) caspase-3 activity. Each data represents mean ± SE of three experiments. (*𝑃<0.05, **𝑃<0.01).

(a)

(b)

(c)

(d)