Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Tab 2

Research Article

A Systems Biology Approach to Uncovering Pharmacological Synergy in Herbal Medicines with Applications to Cardiovascular Disease

Table 2

Comparison of molecular properties between RSM, RAM, RPL, and ROJ.

IndexRSM (mean   SD)RAM (mean   SD)ROJ (mean   SD)RPL (mean   SD)
Total compoundsActive compoundsTotal compoundsActive compoundsTotal compoundsActive compoundsTotal compoundsActive compounds

nHDon2.09
(2.69)
1.95
(3.88)
4.05
(2.86)
3.89
(2.77)
3.22
(3.23)
2.68
(1.49)
5.00
(4.65)
3.42
(2.19)
nHAcc4.23
(4.47)
5.19
(6.78)
7.51
(4.70)
7.91
(4.32)
6.72
(6.22)
6.58
(2.46)
8.50
(7.62)
6.42
(3.70)
MLogP2.45
(2.61)
2.10
(2.28)
0.75
(2.59)
1.18
(2.60)
2.12
(2.48)
1.61
(0.91)
1.28
(3.38)
1.44
(2.57)
MW310.37 (156.93)343.28
(219.76)
411.00 (232.39)438.31
(169.88)
428.72 (262.11)373.42
(120.83)
484.18 (286.37)379.77
(92.05)
RBN3.66
(5.17)
2.09
(4.99)
5.17
(3.68)
5.02
(3.42)
4.99
(4.81)
3.26
(1.45)
6.58
(6.02)
4.08
(3.96)
nCIC2.74
(1.73)
3.72
(1.35)
3.59
(2.66)
4.14
(1.84)
4.05
(3.01)
3.74
(1.52)
3.89 (2.6971)3.58
(1.38)
Hy0.56
(2.00)
0.38
(2.79)
1.92
(2.06)
1.68
(1.95)
1.13
(2.13)
0.74
(0.97)
2.46
(3.28)
1.28
(1.61)
TPSA (Tot)73.61
(76.27)
86.86
(114.01)
120.61
(72.73)
123.18
(69.35)
102.76
(92.12)
100.13
(35.49)
142.01
(125.68)
106.28
(59.74)

*RSM (Radix Salviae Miltiorrhiza), RAM (Radix Astragali Mongolici), RPL (Radix Puerariae lobatae), and ROJ (Radix Ophiopogonis Japonici).

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