Review Article

Traditional Oriental Herbal Medicine for Children and Adolescents with ADHD: A Systematic Review

Table 2

Details of the herbal treatments used in the included studies.

Cheng et al. 2006 [19]Ingredients and amount: Radix Rehmanniae Preparata 6 g, Carapax et Plastrum Testudinis 5 g, Cervi Cornu Degelatinatum 5 g, Rhizoma Acori Tatarinowii 10 g, Radix Polygalae 10 g, Radix et Rhizoma Salviae Miltiorrhizae 10 g, Fructus Schisandrae Chinensis 5 g  
Dosage form: Decoction. The above amount of ingredients are boiled with water to yield 90 mL of decoction.  
Daily dose: 90 mL  
Standardization: not known

Kong et al. 2007 [20]Ingredients and amount: Fructus Lycii 9 g, Flos Chrysanthemi 9 g, Radix Rehmanniae Preparata 24 g, Fructus Corni 12 g, Rhizoma Dioscoreae 12 g, Rhizoma Alismatis 9 g, Cortex Moutan 9 g, Poria 9 g
Dosage form: Pills. It was not clear how many pills were made out of the above amount of herbs.
Daily dose: 9 pills
Drug to extract ratio: not known
Standardization: not known

Lai and Li 2006 [21]Ingredients and amount: Os Draconis 20 g, Carapax et Plastrum Testudinis 10 g, Radix Polygalae 5 g, Rhizoma Acori Tatarinowii 10 g, Fructus Tritici Levis 20 g, Radix Ophiopogonis 10 g, Caulis Polygoni Multiflori 15 g, Radix Codonopsis 15 g, Poria 15 g, Radix Rehmanniae Preparata 15 g, Fructus Schisandrae Chinensis 4 g, Radix et Rhizoma Glycyrrhizae 4 g. Depending on the symptoms of different patients, other herbs might be added but the amount was not specified.
Dosage form: Decoction. 150 mL of decoction was made from the above ingredients.
Daily dose: 150 mL
Standardization: not known

Li and Chen 1999 [22]Ingredients and amount: Fructus Lycii, Radix Rehmanniae Preparata, Fructus Schisandrae Chinensis, Radix et Rhizoma Ginseng, Poria, Radix et Rhizoma Glycyrrhizae. Amount was not specified.
Dosage form: Granules
Daily dose: 3 g or 6 g depending on the age of subject
Drug to extract ratio: not known
Standardization: not known

Li et al. 2004 [23]Ingredients and amount: not known
Dosage form: Granules
Daily dose: 2 doses or 4 doses depending on the age of subject. Amount of granules contained in 1 dose was not specified.
Drug to extract ratio: not known
Standardization: not known

Lin et al. 2007 [24]Ingredients and amount: not known
Dosage form: oral liquid
Daily dose: 30–60 mL
Drug to extract ratio: not known
Standardization: not known

Ma 2007 [16]Ingredients and amount: Flos Magnoliae 10 g, Radix Paeoniae Alba (parched) 30 g, Rhizoma Gastrodiae 8 g, Radix Isatidis 15 g, Radix Scrophulariae 15 g, Massa Medicata Fermentata 6 g, Fructus Crataegi 6 g
Dosage form: Decoction. The amount of decoction yielded from the above ingredients was not specified.
Daily dose: 150 mL or 200 mL depending on the age of subject
Drug to extract ratio: not known
Standardization: not known

Ma et al. 2007 [25]Ingredients and amount: Homonis Placenta, Radix Rehmanniae Preparata, Rhizoma Acori Tatarinowii, Radix Polygalae, Rhizoma Alismatis, Rhizoma Coptidis, and so forth. Amount was not specified.
Dosage form: Granules
Daily dose: 20 g or 30 g depending on the age of subject
Drug to extract ratio: not known
Standardization: not known

Wang and Shi 2003 [26]Ingredients and amount: not known
Dosage form: Oral liquid
Daily dose: 20 mL
Drug to extract ratio: not known
Standardization: not known

Xu 2005 [27]Ingredients and amount: Radix Bupleuri, Radix Peoniae Alba, Ramulus cum Uncis Uncariae, Os Draconis, Margaritifera Concha, Radix Pseudostellariae, Fructus Alpiniae Oxyphyllae, Radix Polygalae, Rhizoma Acori Tatarinowii, Fructus Schisandrae Chinensis, Poria, Radix et Rhizoma Glycyrrhizae Preparata. Amount was not specified.
Dosage form: Granules. 1 g of granules is equivalent to 5 g of herbs.
Daily dose: up to 50 g depending on the body weight of subject
Standardization: not known
L. Yang and J. Yang 2005 [28]Ingredients and amount: Radix Rehmanniae Preparata, Radix Astragali, Radix Peoniae Alba, Os Draconis, Radix Polygalae, Rhizoma Acori Tatarinowii, Fructus Schisandrae Chinensis, Rhizoma Atractylodis Macrocephalae. Amount not specified.
Dosage form: Oral liquid
Daily dose: 60 mL
Standardization: not known

Yu and Wang 2005 [29]Ingredients and amount: Rhizoma Coptidis, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Poria, Rhizoma Atractylodis Macrocephalae, Radix Peoniae Alba, Ramulus cum Uncis Uncariae, Flos Chrysanthemi, Radix Polygalae, Fructus Alpiniae Oxyphyllae, Fructus Corni. Amount was not specified. Other herbs might be added depending on the symptoms of individual subject but the exact ingredients and amount were not given.
Dosage form: Decoction
Daily dose: 1 dose. The amount of 1 dose was not specified.
Drug to extract ratio: not known
Standardization: not known