Chinese Herbal Medicine Paratherapy for Parkinson's Disease: A Meta-Analysis of 19 Randomized Controlled Trials

Table 6

Forest plot of comparison: Chinese herbal medicine versus conventional treatment: UPDRS III scores.

Study or subgroup	Experimental			Control				Mean difference	Mean difference
	Mean	SD	Total	Mean	SD	Total	Weight	IV, random, 95% CI	IV, random, 95% CI
Dou et al. [32]	14.31	7.35	35	20.22	7.65	35	8.4%	−5.91 [−9.42, −2.40]
Fan et al. [31]	14.17	7.344	30	17.1	5436	30	8.6%	−2.93 [−6.20, 0.34]
Hong [30]	22.49	6.17	38	23.77	7.04	38	8.9%	−1.28 [−4.26, 1.70]
Li et al. [33]	30.94	13.99	47	34 53	13.7	44	6.3%	−3.59 [−9.28, 2.10]
Luo et al. [21]	12.46	6.659	22	16.62	7.663	19	7.5%	−4.16 [−8.59, 0.27]
Pan et al. [35]	21.6	10.4	56	24.9	12.7	54	7.6%	−3.30 [−7.65, 1.05]
Wu et al. [34]	16.35	8.52	40	19 86	8.77	40	8.1%	−3.51 [−7.30, 0.28]
Yang et al. [28]	36.9	1.9	55	33.9	2	51	10.4%	3.00 [2.26, 3.74]
Yuan et al. [29]	27.5	5.43	60	2998	493	60	9.8%	−2.48 [−4.34, −0.62]
Zhao et al. [26]	24.43	13.61	75	25.85	15 49	79	7.3%	−1.42 [−6.02, 3.18]
Zheng and Luo [22]	14.17	7.34	30	17.4	6.43	30	8.4%	−3.23 [−6.72, 0.26]
Zhu et al. [25]	29.4	6.8	34	30.6	6.7	31	8.6%	−1.20 [−4.48, 2.08]
Subtotal (95% Cl)			522			511	100.0%	−2.35 [−4.61, −0.08]
Heterogeneity: Tau^2 = 12.73; Chi^2 = 89.22; df = 11 (𝑃<0.00001); l ^2 = 88%
Test for overall effect: 𝑍 = 2.03 (𝑃=0.04)
Total (95% Cl)			522			511	100.0%	−2.35 [−4.61, −0.08]
Heterogeneity: Tau^2 = 12.73; Chi^2 = 89.22; df = 11 (𝑃<0.00001); l ^2 = 88%
Test for overall effect: 𝑍 = 2.03 (𝑃=0.04)
Test for subgroup differences: not applicable