Nausea and vomiting, 5 cases (12.5%). Constipation, 8 cases (20%). Dry mouth, 4 cases (10%). No significant difference in blood and urine routine, liver and kidney function, and ECG before and after treatment ()
Nausea and vomiting, 11 cases (34.4%). Constipation, 13 cases (40.6%). Dry mouth, 5 cases (15.6%). No significant difference in blood and urine routine, liver and kidney function, and ECG before and after treatment ()
No significant changes in blood routine, urine routine, liver and kidney function and ECG before and after treatment. Mild diarrhea, 2 cases. Spontaneous remission after one day
No significant changes in blood routine, urine routine, liver and kidney function and ECG before and after treatment. Adverse reactions in 6 cases (not described in detail)
Gastrointestinal side effects such as mild nausea or upper abdominal pain, 14 cases (). Mild and tolerable. No withdrawal due to adverse events. Constipation, 22 cases, relived after orally taking Maren pills or Glycerine enema. No significant changes in HR, BP, ECG, and liver and kidney function before and after treatment
Gastrointestinal side effects such as mild nausea or upper abdominal pain, 10 cases (). Mild and tolerable. No withdrawal due to adverse events. Constipation, 25 cases, relived after orally taking Maren pills or Glycerine enema. No significant changes in HR, BP, ECG, and liver and kidney function before and after treatment