Neutralisation of Local Haemorrhage Induced by the Saw-Scaled Viper Echis carinatus sochureki Venom Using Ethanolic Extract of Hibiscus aethiopicus L.
Figure 2
(A) Dissected skins of guinea pigs showing oral administrations of the H. aethiopicus extract three hours prior to venom injection (a) control where animals were injected with 75 μg of E. c. sochureki alone; (b, c, and d) represent different concentrations (500, 800, and 1000 mg/kg), respectively, of the H. aethiopicus extract that was orally administered 3 hours prior to venom injection, and animals were sacrificed after 24 hours to examine their skins; (a1 to d1) are the same of the above except that animals where sacrificed and skins where dissected after 32 hours. (B) Chart showing oral administrations of the H. aethiopicus extract three hours prior to venom injection. Neutralisation efficacy of different concentrations of the H. aethiopicus extract when administered orally three hours prior to venom injection (75 μg). The grey and black lines illustrate the gradual neutralisation efficacy of the extract correlated to different concentrations after 24 and 32 hours results, respectively, of animal dissected. *, ** and ***.
