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| Trial | Study carrier | Sample size | Groups | Primary indicator | Results |
|
| She et al. [42] | Healthy female | 49 | Xuehai (SP10), Diji (SP8), Zhongdu (LR6), Sanyinjiao (SP6), Taixi (KI3), Taibai (SP3), Taichong (LR3), Shuiquan (KI5), Xuanzhong (GB39), non-acupoint: located halfway between the stomach and gallbladder meridians lateral to Xuanzhong(GB39) horizontally | Skin temperature of acupoint/non-acupoint at the 1st day of menstruation and the 3rd day after menstruation. | Taixi (KI3) has specific response of menstruation. |
|
| Chen et al. [43] | Healthy undergraduates | 100 | Zusanli (ST36), Fenglong (ST40), Chongyang (ST42), Yinlingquan (SP9), Gongsun (SP4), Taibai (SP3), Guangming (GB37), Qiuxu (GB40) and non-acupoint: the edge of the tibia 1-2 cm lateral to the Zusanli (ST36) horizontally | Changes of average amplitude of gastric electrical activity. | Zusanli (ST36) has greatest impact on gastric function. Acupoints of stomach and spleen meridian have closely relation with stomach. |
|
| Deng et al. [44] | Volunteers | 104 | Bilateral Taiyuan (LU9), Neiguan (PC6), Daling (PC7), non-acupoint one: locates halfway betweenTaiyuan (LU9) and Daling (PC7), non-acupoint two: located halfway between the pericardium and lung meridians lateral to Neiguan (PC6) horizontally | FEV1, MVV | Left Taiyuan (LU9) can reflect the pulmonary function. |
|
| Liu et al. [49] | Patients with coronary heart disease | 50 | Taiyuan (LU9), Shenmen (HT7), Daling (PC7) | Detect the infrared radiation in the spectral range of 1.5–16 μm. | Shenmen (HT7) and Daling (PC7) can reflect the pathological state of myocardial ischemia. |
|
Lai et al. [50],
Zhang et al. [51],
Huang et al. [52] | Healthy volunteers | 36 | Waiguan (TE5); sham needling in TE5; overt placebo needling in TE5; non-acupoint: located at the same level as Waiguan (TE5) and on the midline between the Triple warmer meridian of hand-Shaoyang and the small intestine meridian of hand-Taiyan | Cerebral responses by PET-CT or fMRI detected. | Waiguan (TE5) has relative specific effect in treating dysfunction of ear, cardiovascular disorders, upper limbs paralysis, and blood pressure fluctuation. |
|
| Huang et al. [53, 54] | Ischemic stroke patients | 55 | Waiguan (TE5) needling group, Waiguan (TE5) sham needling group, sham point needling group, sham point sham needling group and non-needling group | Cerebral responses by PET-CT or fMRI detected. | Waiguan (TE5) can specific activate motor execution and vision-related cerebral regions in the healthy hemisphere and the limbic system of the affected hemisphere; can remarkable deactivate the motor execution-related cerebral region, emotion area and cognition region of the affected hemisphere for ischemic stroke patients. |
|
| Zeng et al. [56] | FD patients | 20 | Acupoints of stomach meridian: Liangqiu (ST34), Zusanli (ST36), Fenglong (ST40) and Chongyang (ST42);
Non-acupoints: (1) At the medial arm on the anterior border of the insertion of the deltoid muscle at the junction of the deltoid and biceps muscles; (2) Halfway between the tip of the elbow and the axillae; (3) Ulnar side, halfway between the epicodylus medialis of the humerus and the ulnar side of the wrist; (4) The edge of the tibia 1-2 cm lateral to the Zusanli (ST36) horizontally | Cerebral glycometabolism changes by PET-CT examined. | The more remarkable modulation on the homeostatic afferent network, including the insula, ACC, and hypothalamus, might be the specific mechanism of stomach-specific acupuncture for treating FD. |
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