Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Tab 2

Review Article

A Review of Acupoint Specificity Research in China: Status Quo and Prospects

Table 2

Biological basis studies of acupoint specificity in China.

TrialStudy carrierSample sizeGroupsPrimary indicatorResults

She et al. [42]Healthy female49Xuehai (SP10), Diji (SP8), Zhongdu (LR6), Sanyinjiao (SP6), Taixi (KI3), Taibai (SP3), Taichong (LR3), Shuiquan (KI5), Xuanzhong (GB39), non-acupoint: located halfway between the stomach and gallbladder meridians lateral to Xuanzhong(GB39) horizontallySkin temperature of acupoint/non-acupoint at the 1st day of menstruation and the 3rd day after menstruation.Taixi (KI3) has specific response of menstruation.

Chen et al. [43]Healthy undergraduates100Zusanli (ST36), Fenglong (ST40), Chongyang (ST42), Yinlingquan (SP9), Gongsun (SP4), Taibai (SP3), Guangming (GB37), Qiuxu (GB40) and non-acupoint: the edge of the tibia 1-2 cm lateral to the Zusanli (ST36) horizontallyChanges of average amplitude of gastric electrical activity.Zusanli (ST36) has greatest impact on gastric function. Acupoints of stomach and spleen meridian have closely relation with stomach.

Deng et al. [44]Volunteers104Bilateral Taiyuan (LU9), Neiguan (PC6), Daling (PC7), non-acupoint one: locates halfway betweenTaiyuan (LU9) and Daling (PC7), non-acupoint two: located halfway between the pericardium and lung meridians lateral to Neiguan (PC6) horizontallyFEV1, MVVLeft Taiyuan (LU9) can reflect the pulmonary function.

Liu et al. [49]Patients with coronary heart disease50Taiyuan (LU9), Shenmen (HT7), Daling (PC7)Detect the infrared radiation in the spectral range of 1.5–16 μm.Shenmen (HT7) and Daling (PC7) can reflect the pathological state of myocardial ischemia.

Lai et al. [50],
Zhang et al. [51],
Huang et al. [52]
Healthy volunteers36Waiguan (TE5); sham needling in TE5; overt placebo needling in TE5; non-acupoint: located at the same level as Waiguan (TE5) and on the midline between the Triple warmer meridian of hand-Shaoyang and the small intestine meridian of hand-Taiyan Cerebral responses by PET-CT or fMRI detected.Waiguan (TE5) has relative specific effect in treating dysfunction of ear, cardiovascular disorders, upper limbs paralysis, and blood pressure fluctuation.

Huang et al. [53, 54]Ischemic stroke patients55Waiguan (TE5) needling group, Waiguan (TE5) sham needling group, sham point needling group, sham point sham needling group and non-needling groupCerebral responses by PET-CT or fMRI detected.Waiguan (TE5) can specific activate motor execution and vision-related cerebral regions in the healthy hemisphere and the limbic system of the affected hemisphere; can remarkable deactivate the motor execution-related cerebral region, emotion area and cognition region of the affected hemisphere for ischemic stroke patients.

Zeng et al. [56]FD patients20Acupoints of stomach meridian: Liangqiu (ST34), Zusanli (ST36), Fenglong (ST40) and Chongyang (ST42);
Non-acupoints: (1) At the medial arm on the anterior border of the insertion of the deltoid muscle at the junction of the deltoid and biceps muscles; (2) Halfway between the tip of the elbow and the axillae; (3) Ulnar side, halfway between the epicodylus medialis of the humerus and the ulnar side of the wrist; (4) The edge of the tibia 1-2 cm lateral to the Zusanli (ST36) horizontally
Cerebral glycometabolism changes by PET-CT examined.The more remarkable modulation on the homeostatic afferent network, including the insula, ACC, and hypothalamus, might be the specific mechanism of stomach-specific acupuncture for treating FD.

Notes: FEV1:1s forced expiratory volume; MVV: maximal voluntary ventilation.

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