Antioxidant and Protective Effects of Bupleurum falcatum on the L-Thyroxine-Induced Hyperthyroidism in Rats

Figure 5

Representative histopathological profiles on the on the epididymal fat pads of intact control (a), LT4 control (b), PTU 10 mg/kg (c), BR 300 (d), 150 (e), and 75 (f)  mg/kg treated rats. LT4 treatment-related decreases of adipocyte diameters were dramatically inhibited by PTU 10 mg/kg, BR 300, 150 and 75 mg/kg administration. BR: aqueous Bupleuri Radix extracts; LT4: levothyroxine; PTU: propylthiouracil. All H&E stain; scale bars = 80 μm.

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