Antioxidant and Protective Effects of Bupleurum falcatum on the L-Thyroxine-Induced Hyperthyroidism in Rats

Table 1

Relative organ weights in the LT4 and test materials-treated rats.

Groups	Relative organ weights (%)
	Thyroid gland (mg/g of body weight)	Liver (g/g of body weight)	Epididymal fat (g/g of body weight)
Controls
Intact	3.19±0.41	3.47±0.34	1.51±0.23
LT4	2.03±0.45^a	2.46±0.25^c	0.62±0.17^a
Reference
PTU 10 mg/kg	3.51±0.72^b	3.87±0.90^e	1.16±0.24^ab
BR treated
300 mg/kg	4.01±0.62^ab	3.99±0.49^de	1.44±0.19^b
150 mg/kg	3.36±0.48^b	3.72±0.45^e	1.14±0.13^ab
75 mg/kg	3.13±0.35^b	3.52±0.37^e	0.90±0.17^ab

Values are expressed mean±S.D. of eight rats. BR: aqueous Bupleuri Radixextracts; LT4: levothyroxine; PTU: propylthiouracil. ^a𝑃<0.01 as compared with intact control by LSD test; ^b𝑃<0.01 as compared with LT4 control by LSD test; ^c𝑃<0.01 and ^d𝑃<0.05 as compared with intact control by MW test; ^e𝑃<0.01 as compared with LT4 control by MW test.