Ferulsinaic Acid Modulates SOD, GSH, and Antioxidant Enzymes in Diabetic Kidney
Table 1
Physiological, biochemical, and renal functional parameters of the rats.
Normal control
DN
DN + MF
DN + FA1
DN + FA2
DN + FA3
Initial body weight, g
Final body weight, g
Glucose, mmol/L
Kidney/body weight, g/g, ×10−3
BUN, mmol/L
Serum creatinine, mmol/L
Ccr mL min−1 kg−1
U prot, mg/24 h
Serum sodium, mmol/L
Serum potassium, mmol/L
Serum IL-6, g/mL
Data are expressed as the means ± SD. DN: diabetes group; FA1, FA2, FA3, and MF: diabetic rats treated with low dose (5 mg/kg) of FA (DN + FA1), middle dose (50 mg/kg) of FA (DN + FA2), high dose (500 mg/kg) of FA (DN + FA3), and (125 mg/kg) of metformin (DN + MF), respectively. Each group consisted of 10 animals. .05 versus normal control group; versus DN group; versus DN + FA1 group; versus DN + FA2 group.