Early Blockade of TLRs MyD88-Dependent Pathway May Reduce Secondary Spinal Cord Injury in the Rats
Figure 3
Western blot analysis for proinflammatory cytokines and phospho-p38 MAP kinase. TNF-α, IL-1β, and P-p38 MAP kinase proteins in the spinal cord were detected at 7 d after compression SCI in both MIP- and CP-treated groups. Levels of TNF-α (a), IL-1β (b), and P-p38 MAP kinase (c) were significantly decreased in MIP group, respectively, compared with CP group. Levels of proteins expression were presented as the ratio of the band area integral values under absorption curve of each protein with the area integral value s of β-actin. The quantified data are represented 4 animals per group (*).
