Berberine in the Treatment of Type 2 Diabetes Mellitus: A Systemic Review and Meta-Analysis

Table 2

Characteristics of included trials (three-armed and four-armed parallel group).

Author	Number of patients in each group				Intervention in each group
	1	2	3	4	1	2	3	4	Duration (wks)	Outcomes
Cao 2007 [19]	30	30	30	30	LM	LM, Ber	LM, Ber, Qi	LM, Met	12	FBG, PPG, HbA1c, FINS, TC, TG, LDL-C, HDL-C, AE
Li and Liu 2007 [20]	51	51	50		Ber	Ber, Glip	Glip		8	FBG, PPG, HbA1c, FINS, TC, TG, LDL-C, HDL-C, AE
Li 2008 [13]	17	18	17		Ber	Ber, Met	Met		12	FBG, PPG, AE
Zhang et al. 2010 [11]	50	26	21		Ber	Met	Ros		8	FBG, HbA1c, TG, AE
Xiang et al. 2011 [21]	20	20	20		LM	LM, Ber	LM, Asp		12	FBG, PPG, HbA1c, TC, TG, LDL-C, AE

Note: AE: adverse effect; Asp: aspirin; Ber: berberine; Glip: glipizide; LM: lifestyle modification; Met: metformin; Qi: Qihuang capsule.