Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Fig 5

Research Article

Terminalia catappa Exerts Antimetastatic Effects on Hepatocellular Carcinoma through Transcriptional Inhibition of Matrix Metalloproteinase-9 by Modulating NF-κB and AP-1 Activity

Figure 5

Critical role of AP-1 and NF- B in TCE-induced transcriptional inhibition of MMP-9 in Huh7 cells. Huh7 cells were treated with TCE (0, 100  g/mL) for 24 h and then the nuclear fraction was prepared as described in Section 2. ((a) and (b)) Levels of AP-1 and NF- B in the nucleus were immunodetected with AP-1- and NF- B-, specific antibodies, respectively.

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