Association of the Apolipoprotein A5 Gene −1131T>C Polymorphism with Serum Lipids in Korean Subjects: Impact of Sasang Constitution

Table 2

Clinical and biochemical characteristics according to the APOA5 −1131T>C polymorphism and association of the APOA5 −1131T>C polymorphism with BMI, FBG, and serum lipid variables in the study population.

Variables	Mean ± SD			Multiple regression
	TT (𝑛=765)	TC (𝑛=712)	CC (𝑛=142)	Slope	95% CI of slope		P-value
BMI (kg/m^2)	23.6 ± 3.42	23.37 ± 3.31	23.93 ± 3.31	0.04	−0.211	0.291	0.755
FBG (mg/dL)	99.4 ± 29.95	98.02 ± 26.29	96.55 ± 18.37	−1.185	−3.245	0.875	0.259
HDL-C (mg/dL)	46.91 ± 11.68	45.76 ± 12.17	43.44 ± 10.33	−1.602	−2.481	−0.723	3.61 𝐄− 04
LDL-C (mg/dL)	107.28 ± 28.47	105.49 ± 30.98	108.95 ± 28.76	−0.022	−2.247	2.203	0.984
Total cholesterol (mg/dL)	188.5 ± 32.68	186.87 ± 35.45	192.87 ± 35.39	0.845	−1.728	3.417	0.52
TG (mg/dL)	120.85 ± 69.71	131.66 ± 86.23	166.8 ± 122.26	18.792	12.616	24.968	2.94 𝐄− 09

Values are indicated as the mean ± standard deviation.
P-value: multiple regression analysis result.
Bold indicates statistically significant (𝑃<0.05).
Abbreviations: CI, confidence interval; BMI, body mass index; FBG, fasting blood glucose HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglyceride.