Association of the Apolipoprotein A5 Gene −1131T>C Polymorphism with Serum Lipids in Korean Subjects: Impact of Sasang Constitution

Table 3

Association of the APOA5 −1131T>C polymorphism with BMI, FBG, and serum lipid variables according to gender in study population.

Variables	Gender	Mean ± SD			Multiple regression
		TT	TC	CC	Slope	95% CI of slope		P-value
BMI (kg/m^2)	Male	24.14 ± 3.41	23.84 ± 3.29	24.26 ± 2.98	−0.058	−0.469	0.353	0.781
	Female	23.3 ± 3.39	23.09 ± 3.3	23.72 ± 3.51	0.052	−0.26	0.363	0.744
FBG (mg/dL)	Male	103.81 ± 35.87	101.16 ± 25.92	98.65 ± 20.74	−2.149	−5.866	1.568	0.257
	Female	97.01 ± 25.91	96.12 ± 26.36	95.14 ± 16.58	−0.815	−3.231	1.601	0.508
HDL-C (mg/dL)	Male	42.82 ± 10.46	41.29 ± 10.31	38.32 ± 7.09	−2.124	−3.362	−0.887	0.001
	Female	49.13 ± 11.72	48.48 ± 12.42	46.88 ± 10.76	−0.987	−2.106	0.131	0.084
LDL-C (mg/dL)	Male	107.79 ± 28.19	104.48 ± 30.24	104.67 ± 27.97	−2.262	−5.882	1.358	0.22
	Female	107 ± 28.65	106.1 ± 31.44	111.82 ± 29.09	1.177	−1.615	3.969	0.408
Total cholesterol (mg/dL)	Male	186.3 ± 32.22	183.3 ± 35.19	188.67 ± 36.28	−0.481	−4.71	3.747	0.823
	Female	189.7 ± 32.89	189.04 ± 35.46	195.69 ± 34.71	1.62	−1.582	4.822	0.321
TG (mg/dL)	Male	135.58 ± 71.94	152.35 ± 95.84	209.95 ± 163.59	30.208	18.416	42	6.47 𝐄− 07
	Female	112.86 ± 67.2	119.1 ± 77.28	137.87 ± 71.68	10.355	3.752	16.958	0.002

Values are indicated as the mean ± standard deviation.
P-value: multiple regression analysis result.
Bold indicates statistically significant (𝑃<0.05).
Abbreviations: CI, confidence interval; BMI, body mass index; FBG, fasting blood glucose HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglyceride.