Association of the Apolipoprotein A5 Gene −1131T>C Polymorphism with Serum Lipids in Korean Subjects: Impact of Sasang Constitution

Table 4

Clinical and biochemical characteristics of the study subjects according to SCG.

Variables

Mean ± SD

P-value^a

P-value^b

SY

SE

TE

Male (𝑛=186)

Female (𝑛=360)

Total (𝑛=546)

P-value^c

Male (𝑛=141)

Female (𝑛=264)

Total (𝑛=405)

P-value^c

Male (𝑛=268)

Female (𝑛=400)

Total (𝑛=668)

P-value^c

Age (years)

49.39 ± 14.07

46.91 ± 14.65

47.76 ± 14.49

0.058

44.14 ± 15.89

46.65 ± 14.63

45.77 ± 15.11

0.111

47.32 ± 14.77

51.44 ± 14.86

49.78 ± 14.95

4.62𝐸−04

8.55𝐸−05

—

BMI (kg/m^2)

23.68 ± 3.03

22.4 ±; 2.7

22.84 ± 2.88

7.07𝐸−07

21.52 ± 2.78

21.33 ± 2.56

21.4 ± 2.63

0.48

25.57 ± 2.86

25.26 ± 3.31

25.39 ± 3.14

0.208

4.09𝐸−97

7.63𝐸−92

FBG (mg/dL)

104.25 ± 31.39

96.46 ± 28.72

99.11 ± 29.86

0.004

97.09 ± 25.15

91.4 ± 13.4

93.38 ± 18.53

0.003

103.28 ± 32.09

99.82 ± 27.79

101.21 ± 29.62

0.139

2.92𝐸−05

7.58𝐸−04

HDL-C (mg/dL)

41.81 ± 10.81

49.21 ± 11.78

46.67 ± 11.98

2.92𝐸−12

45.05 ± 10.09

51.34 ± 11.99

49.15 ± 11.74

1.84𝐸−07

39.85 ± 9.34

46.41 ± 11.69

43.78 ± 11.27

5.49𝐸−14

1.19𝐸−12

1.57𝐸−09

LDL-C (mg/dL)

103.41 ± 29.5

105.76 ± 29.37

104.96 ± 29.41

0.378

101.81 ± 26.97

101.5 ± 28.06

101.61 ± 27.65

0.916

109.99 ± 29.53

111.77 ± 30.95

111.05 ± 30.38

0.457

6.58𝐸−07

1.08𝐸−05

Total cholesterol (mg/dL)

183.85 ± 33.74

188.81 ± 33.65

187.12 ± 33.73

0.104

179.27 ± 32.17

183.86 ± 31.48

182.26 ± 31.76

0.166

189.19 ± 34.67

194.9 ± 35.69

192.61 ± 35.37

0.041

5.97𝐸−06

3.77𝐸−05

TG (mg/dL)

158.58 ± 104.8

114.1 ± 67.92

129.25 ± 84.93

4.01𝐸−09

111.72 ± 58.15

96.5 ± 49.36

101.8 ± 53.02

0.006

164.82 ± 102.87

134.77 ± 84.02

146.83 ± 93.14

3.98𝐸−05

7.00𝐸−17

1.11𝐸−13

Values are indicated as the mean ± standard deviation.
P-value^a: analysis of variance (ANOVA) result.
P-value^b: analysis of covariance (ANCOVA) result.
P-value^c: Student's 𝑡-test result.
Abbreviations: SY, So-Yang; SE, So-Eum; TE, Tae-Eum; BMI, body mass index; FBG, fasting blood glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglyceride.