Evidence-Based Complementary and Alternative Medicine

Research Article

Association of the Apolipoprotein A5 Gene −1131T>C Polymorphism with Serum Lipids in Korean Subjects: Impact of Sasang Constitution

Table 5

Association of the APOA5 −1131T>C polymorphism with BMI, FBG, and serum lipid variables according to SCG in study population.


Variables	Constitution	Mean ± SD			Multiple regression
Variables	Constitution	TT	TC	CC	Slope	95% CI of slope		P-value

BMI (kg/m²)	SY	22.81 ± 3.12	22.77 ± 2.65	23.25 ± 2.66	0.132	−0.224	0.489	0.465
	SE	21.56 ± 2.7	21.21 ± 2.5	21.63 ± 3.13	−0.098	−0.518	0.322	0.647
	TE	25.42 ± 3.12	25.35 ± 3.17	25.38 ± 3.22	−0.049	−0.412	0.314	0.79

FBG (mg/dL)	SY	100.23 ± 32.1	98.06 ± 29.59	98.31 ± 17.52	−1.256	−5.022	2.51	0.513
	SE	93.4 ± 20.04	93.34 ± 17.35	93.54 ± 16.09	0.112	−2.862	3.086	0.941
	TE	102.25 ± 32.46	101.17 ± 28.02	96.19 ± 19.92	−2.45	−5.826	0.926	0.155

HDL-C (mg/dL)	SY	47.62 ± 11.43	46.21 ± 12.93	44.26 ± 9.77	−1.602	−3.043	−0.16	0.03
	SE	49.24 ± 12.07	49.42 ± 11.55	46.29 ± 10.65	−0.537	−2.368	1.294	0.564
	TE	44.97 ± 11.35	42.91 ± 11.24	41.69 ± 10.5	−1.659	−2.883	−0.436	0.008

LDL-C (mg/dL)	SY	106.75 ± 29.92	103.34 ± 28.71	103.39 ± 29.99	−1.873	−5.562	1.816	0.319
	SE	100.35 ± 26.6	101.7 ± 28.43	110.71 ± 28.78	3.957	−0.482	8.396	0.081
	TE	111.76 ± 27.56	109.82 ± 33.88	112.98 ± 27.36	−0.37	−3.9	3.159	0.837

Total cholesterol (mg/dL)	SY	188.63 ± 33.64	184.87 ± 33.12	189.57 ± 36.75	−0.591	−4.836	3.654	0.785
	SE	180.76 ± 31.32	182.46 ± 32.27	192.25 ± 30.32	4.717	−0.395	9.829	0.07
	TE	192.94 ± 31.91	191.51 ± 38.77	195.89 ± 36.24	0.419	−3.683	4.52	0.841

TG (mg/dL)	SY	117.68 ± 69.29	130.47 ± 83.47	179.48 ± 130.64	24.43	14.212	34.648	3.36 06
	SE	98.86 ± 51.96	102.62 ± 50.78	118.08 ± 74.47	7.99	−0.183	16.163	0.055
	TE	136.31 ± 75.28	152.41 ± 100.8	174.38 ± 126.37	17.155	6.696	27.614	0.001

Values are indicated as the mean ± standard deviation.
P-value: multiple regression analysis result.
Bold indicates statistically significant ().
Abbreviations: CI, confidence interval; SY, So-Yang; SE, So-Eum; TE, Tae-Eum; BMI, body mass index; FBG, fasting blood glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglyceride.