Inhibition of Advanced Glycation End-Product Formation by Origanum majorana L. In Vitro and in Streptozotocin-Induced Diabetic Rats

Table 1

The inhibitory effects of methanol extract from O. majorana (OM) and aminoguanidine on the formation of advanced glycation end-products (AGEs), in vitro induced by glucose, methylglyoxal and ribose.

Inducer	Treatment	AGEs; IC50 (mg/mL)
Glucose	Methanol extract (OM)	0.310±0.054
	Aminoguanidine	0.323±0.075
	Phloroglucinol	0.070±0.0032
Methylglyoxal	Methanol extract (OM)	0.190±0.028
	Aminoguanidine	0.195±0.015
	Phloroglucinol	0.060±0.0083
Lysozyme/ribose	Methanol extract (OM)	64.7%
	Aminoguanidine	58.3%

Data are mean ± standard deviation of triplicate tests.