Research Article
Antibacterial Activities of Selected Cameroonian Plants and Their Synergistic Effects with Antibiotics against Bacteria Expressing MDR Phenotypes
Table 4
Minimal inhibitory concentration (μg/mL) of methanol extracts from the studied plants and ciprofloxacin.
| | Bacteria strains | Plants extractsa and MIC (μg/mL) in the absence and presence of PAβN (in bracket) | | CAF | PNF | ASB1 | ASB2 | BCF | PNS | CMF | GKS | GLS | CPS | ACB1 | ACB2 | CIP |
| | E. coli | | | | | | | | | | | | | | | ATCC8739 | — | 1024 | — | — | — | — | — | 512 | 512 | — | — | — | <0.5 | | ATCC10536 | — | 1024 | — | — | — | 1024 | — | 512 | 512 | 1024 | — | — | 64 | | W3110 | 1024 (1024) | 512 (512) | — | — | — | — (512) | — (1024) | 512 (256) | 256 (128) | — | — | — (1024) | <0.5 (<0.5) | | MC4100 | — | 512 | — | — | — | 1024 | — | 512 | 256 | — | 1024 | 1024 | 32 | | AG100A | 1024 | 512 (128) | — | — (512) | — | — (1024) | — | 1024 (1024) | 256 (64) | 1024 (1024) | — | — | 16 (8) | | AG100Atet | 1024 (1024) | 1024 (512) | — | — | — | — | — | 256 (256) | 512 (512) | 1024 (1024) | 1024 (1024) | — | 32 (8) | | AG102 | — | 512 (128) | — | — (1024) | — (1024) | — (1024) | — (1024) | 256 (64) | 512 (256) | 512 (512) | — | — | 32 (16) | | AG100 | — | 512 | — | — | 1024 | — | — | 256 | 256 | 1024 | — | 1024 | 0.5 | | E. aerogenes | | | | | | | | | | | | | | | ATCC13048 | — | 512 | — | — | — | — | — | 512 | 256 | — | — | — | 1 | | EA294 | — | 1024 | — | — | — | — | — | 512 | 256 | — | 1024 | — | 64 | | CM64 | 1024 | 512 | — | — | 1024 | — | 1024 | 256 | 256 | — | 512 | — | 32 | | EA3 | — | 512 | — | — | — | — | — | 512 | 256 | — | — | — | 32 | | EA298 | — | — (512) | — | — | — | — | — | 512 (128) | 256 (128) | — | — | — | 1 (<0.5) | | EA27 | 1024 (1024) | 512 (512) | — | — | — | — | — | 256 (256) | 256 (256) | 1024 (1024) | — | — | 1 (<0.5) | | EA289 | — | 1024 (1024) | — | — | — | — | — (1024) | 512 (512) | 512 (256) | — | — | — | 64 (32) | | K. pneumoniae | | | | | | | | | | | | | | | ATCC11296 | 1024 (1024) | 512 (256) | — | — (1024) | — (1024) | — | — | 512 (512) | 256 (128) | — (512) | — | — | <0.5 (<0.5) | | KP55 | 512 (512) | 512 (256) | — | — | — | — | — | 512 (512) | 128 (128) | 1024 (1024) | 1024 (1024) | — (1024) | 32 (4) | | KP63 | — | 512 | — | — | — | — | — | 512 | 512 | — | — | — | 32 | | K2 | — | 1024 | — | — | — | — | — | 512 (256) | 256 (128) | 1024 (1024) | — (512) | — | 32 (8) | | K24 | 512 | 512 | — | — | — | — | — | 512 | 256 | 1024 | 1024 | — | 32 | | P. aeruginosa | | | | | | | | | | | | | | | PA01 | — | 1024 (1024) | — | — | — | — | — | 512 (512) | 512 (512) | — | — | — | 32 (4) | | PA124 | — | 512 | — | — | — | — | — | 1024 | 256 | 1024 | — | — | 128 | | P. stuartii | | | | | | | | | | | | | | | ATCC29916 | 1024 (1024) | 1024 (1024) | — | — | — | — | — | 512 (512) | 256 (128) | 1024 (1024) | — | — | >64 (16) | | NAE16 | 1024 | 512 | — | — | — | 1024 | — | 256 | 256 | 1024 | 1024 | — | 64 | | PS2636 | — | 1024 | — | — | — | — | — | 128 | 128 | — | — | — | 64 | | PS299645 | 1024 (1024) | 1024 (1024) | — | | 1024 (1024) | 1024 (1024) | 1024 (1024) | 256 (256) | 128 (128) | 1024 (1024) | — | — | <0.5 (<0.5) | | E. cloacae | | | | | | | | | | | | | | | BM47 | — | 256 | — | — | — | — | — | 256 | 256 | — | — | 1024 | 64 | | ECCI69 | 1024 | 512 | — | — | 1024 | — | 1024 | 128 | 128 | — | — | — | 128 | | BM67 | 1024 | 512 | — | — | — | — | — | 256 | 256 | 1024 | 1024 | — | 32 |
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(—) MIC greater than 1024 μg/mL; aExtract from CAF: Cola acuminata fruit; PNF: Picralima nitida fruits; ASB1: Allium sativum dry bulbs; ASB2: Allium sativum fresh bulbs; BCF: Buchholsia coriacea fruits; PNS: Picralima nitida seeds; CMF: Citrus médica fruits juice; GKS: Garcinia kola seeds; GLS: Garcinia lucida seeds; CPS: Carica papaya seeds; ACB1: Allium cepa fresh bulbs; ACB2: Allium cepa dry bulbs; CIP: ciprofloxacin.
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