A Herbal Composition of Semen Hoveniae, Radix Puerariae, and Fructus Schisandrae Shows Potent Protective Effects on Acute Alcoholic Intoxication in Rodent Models

Table 5

Comparison of the anti-inebriation effects and changes in hepatic antioxidative capacity induced by SRFE and SHE in acutely inebriated mice.

Groups	Doses	Ethanol	Loss of the righting reflex	Recovery of the righting reflex	Serum ethanol	Hepatic MDA
	(g/kg)	(g/kg)	(mean rank)	(mean rank)	(g/L)	(𝜇mol/g prot)
Model	—	7.70	19.22	31.75	3.77 ± 0.22	1.37 ± 0.05
SRFE	0.24	7.70	29.75^*	18.91^**	2.05 ± 0.5^**	1.21 ± 0.03^*
SHE	0.24	7.70	26.87	23.40	3.35 ± 0.11	1.31 ± 0.04

SRFE: Semen Hoveniae, Radix Puerariae, and Fructus Schisandrae extract; SHE: Semen Hoveniae extract; MDA: malondialdehyde. Means ± S.E.M., 𝑛=12. ^∗𝑃<0.05, ^∗∗𝑃<0.01, versus model.