Research Article

Fisetin Inhibits Hyperglycemia-Induced Proinflammatory Cytokine Production by Epigenetic Mechanisms

Figure 5

Effect of fisetin on the interaction of p300 with acetylated p65 and TNF-α. Cells were treated with fisetin for 48 h and then nuclear lysates were prepared. p300 was immunoprecipitated, and interaction with acetylated p65 and TNF-α was assessed by western blotting. The immunoblots shown here are representative of 3 independent experiments.
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