Research Article

Dietary Supplementation of Female Rats with Elk Velvet Antler Improves Physical and Neurological Development of Offspring

Table 1

Effects of maternal dietary EVA supplementation on the onset and completion of neuromotor skill and neurological reflex acquisition in rat pups.

Signs2Day of onset1Day of completion1
MaleFemaleMaleFemale
ControlEVAControlEVAControlEVAControlEVA

Righting reflex2.0 (0.01)1.0 (0.05)2.0 (0.02)1.1 (0.07)4.9 (0.25)3.1 (0.12)4.9 (0.26)3.1 (0.12)
Negative geotaxis4.1 (0.18)4.0 (0.20)4.0 (0.20)4.0 (0.20)6.9 (0.27)6.8 (0.28)6.5 (0.30)6.5 (0.30)
Cliff avoidance6.6 (0.30)6.3 (0.26)6.9 (0.20)6.9 (0.33)8.0 (0.35)6.6 (0.28)7.9 (0.32)7.9 (0.35)
Acoustic startle11.0 (0.45)9.4 (0.40)11.0 (0.45)9.4 (0.40)12.0 (0.50)11.0 (0.45)12.0 (0.50)11.6 (0.51)
Supported standing8.0 (0.34)7.6 (0.33)8.0 (0.34)7.6 (0.33)11.2 (0.65)10.0 (0.00)*10.9 (0.48)9.1 (0.34)*
Unsupported standing15.9 (0.66)14.9 (0.65)*15.8 (0.56)15.0 (0.70)17.9 (0.66)15.8 (0.30)*17.9 (0.66)16.1 (0.40)*

1Data are expressed as mean ± standard error of man (SEM).
2The acquisition of various reflexes (yes/no) was assessed at specific postnatal ages, for example, Righting Reflex at PND 1–5, Negative Geotaxis at PND 4–6, Cliff Avoidance at PND 6–8, Acoustic Startle at PND 9–12, Supported standing at PND 7–11, and Unsupported standing at PND 15–18.
*Significant ( ) differences between control and EVA groups (within gender) in the onset or completion of physical and neurological signs of development.