Research Article

Can Combination Therapy of Conventional and Oriental Medicine Improve Poststroke Aphasia? Comparative, Observational, Pragmatic Study

Table 2

Patient characteristics in the 2 groups.

COT group
( 𝑛 = 4 7 )
OLT group
( 𝑛 = 3 0 )
𝑃 -value

Gender, male (%)31 (66)14 (46.7)0.104
Age, yr (SD, median)54.5 (12.1, 54)52.5 (17.6, 55.5)0.790
Education, yr (SD, median)10.8 (5.1, 12)11.2 (3.8, 12)0.918
Handedness, right (%)46 (97.9)30 (100)1.000
Treatment period from onset, day (SD, median)48 (45.4, 29)41 (28.7, 39)0.954
Duration of treatment, weeks (SD, median)6.6 (7.1, 4.9)7.8 (5.7, 6.4)0.104
Hypertension (%)31 (65.96)20 (66.67)1.000
Diabetes mellitus (%)12 (25.53)3 (10)0.140
Dyslipidemia (%)8 (17.02)3 (10)0.513
Heart disease (%)7 (14.89)4 (13.33)1.000
AQ scores  
(SD, median)
28.1 (25.6, 19.2)26.7 (26.2, 19)0.875
 Total score5.5 (5.1, 3)5.7 (5.4, 5)0.757
Spontaneous speech 3.3 (2.8, 2)3.4 (3, 3)0.987
  Content delivery2.2 (2.4, 1)2.5 (2.8, 1.5)0.928
  Fluency3.6 (2.9, 3.2)3.6 (2.7, 3.1)0.979
Comprehension 32.1 (17.9, 33)29.6 (18.9, 32)0.645
  Yes-no21.1 (20.9, 11)21.9 (20.4, 18.5)0.892
  Auditory verbal comprehension19.8 (23.4, 10)19.7 (21.4, 12)0.834
  Command performance3.3 (3.6, 1.2)2.4 (3.4, 0.6)0.179
Repetition 1.9 (2.6, 0.5)1.6 (2.6, 0.2)0.405
Naming 12.9 (17.9, 4)11.4 (18.1, 0.5)0.457
  Naming things1.2 (2.8, 0)1.2 (2.5, 0)0.510
  Control word association2.5 (3.6, 0)2 (3.3, 0)0.472
  Sentence completion1.9 (3.3, 0)1.7 (3.3, 0)0.670
  Sentence answers

COT group: group that received language therapy with oriental medicine therapy.
OLT group: group that received language therapy only.
AQ: aphasia Quotient.
𝑃 value was obtained by the Mann-Whitney 𝑈 test (age, education, treatment period from onset, duration of treatment, and AQ scores) and Fisher’s exact test (gender and handedness).
SD: standard deviation.