Research Article

Effects of Thymol and Carvacrol, Constituents of Thymus vulgaris L. Essential Oil, on the Inflammatory Response

Figure 4

Effect of CVL on ear edema (a) and myeloperoxidase activity (MPO) (b) induced by croton oil in ear tissues from mice. The animals ( ) were treated topically with carvacrol, indomethacin (Indo), or dexamethasone (Dex) 1 h before croton oil application (10  L/ear). Dex (0.1 mg/ear) or Indo (0.5 mg/ear) were used as anti-inflammatory drugs (positive control). The right ears received only the vehicle (Basal). Data are mean ± SEM weight of the ears (a) or MPO activity (b), 4 hours after application of croton oil, # , compared to the control group (croton oil) (ANOVA, Tukey’s test).
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(a)
657026.fig.004b
(b)