Review Article

Acupuncture for Treatment of Autism Spectrum Disorders

Table 1

Summary of the 27 clinical studies.

Study by referenceNumber of subjectsControlsRandomizationBlinded*Description of subject dropoutJadad Scores

Wong et al. [43]55YesYesDB*Yes5
Zhang et al. [22]30YesYesNoYes3
Allam et al. [45]20YesYesSB*No3
Li et al. [41]70YesYesSB*No2
Wong and Sun [44]50YesYesSB*No2
Yan et al. [30]40YesYesNoNo2
Zhang et al. [25]30YesYesNoYes2
Ma et al. [21]44YesYesNoNo1
Yuan et al. [16, 19, 24], Wu et al. [23]202YesNoNoYes1
Liu and Yuan [32]67YesYesNoNo1
Wang et al. [31]60YesYesNoNo1
Zhou and Zhang [37]30YesYesNoNo1
Li et al. [39]38YesYesNoNo1
Xie [26]182YesNoNoNo0
Yuan et al. [17]69YesNoNoNo0
Yuan et al. [20]49YesNoNoNo0
Yuan et al. [18]40YesNoNoNo0
Liu et al. [28]38NoNoNoNo0
H. Wu and Z. Y. [7], Wu [36]35NoNoNoNo0
Luo et al. [27]35NoNoNoNo0
Jia et al. [34]34NoNoNoNo0
Xi et al. [29]32NoNoNoNo0
Zhao et al. [42]24NoNoNoNo0
Ju and Feng [33]13NoNoNoNo0
Zhang [38]12NoNoNoNo0
Jiang and Wang [35]11NoNoNoNo0
Wang [40]11NoNoNoNo0

Total 27 studiesRanges 11–20217/27 studies had controls12/27 studies randomized4/27 studies were blinded4/27 studies described dropoutsJadad score
5 1 study
3 2 studies
2 4 studies
1 16 studies

*DS: double blinded, SB: single blinded.