Inchingorei-san (TJ-117) and Artemisiae Capillaris Herba Induced Prolonged Survival of Fully Mismatched Cardiac Allografts and Generated Regulatory Cells in Mice
Figure 3
Evidence of induction of alloproliferative hyporesponsiveness by Artemisiae Capillaris Herba (ACH). (a) Results of cell-proliferation assays in mixed leukocyte cultures (MLCs). The data shown are mean ± SD values derived from samples from 5 mice in each group. *P < 0.01 for difference between 2 groups. (b)–(e) Levels of cytokines in MLCs. Levels of interleukin (IL)-2 (b), IL-4 (c), IL-10 (d), and interferon (IFN)-γ (e) in the MLCs were assessed by enzyme-linked immunosorbent assays. Data are shown as mean ± SD values derived from samples from 5 mice in each group. *P < 0.01 for difference between 2 groups.
