A Chinese Herbal Formula to Improve General Psychological Status in Posttraumatic Stress Disorder: A Randomized Placebo-Controlled Trial on Sichuan Earthquake Survivors
Table 4
XTJYF treatment effect on primary and secondary outcomes.(1)
SCL-90-R factor
XTJYF (N = 123)
Placebo (N = 122)
Effect size(2)
P (3)
Mean (95% CI)
Mean (95% CI)
Primary outcomes
Global severity index
0.30 (0.24–0.37)
0.15 (0.09–0.21)
0.424
0.001
Positive symptom total index
6.66 (4.58–8.73)
3.52 (1.62–5.41)
0.284
0.028
Positive symptom distress index
0.38 (0.30–0.45)
0.19 (0.12–0.26)
0.448
0.001
Secondary Outcomes
Somatization
0.34 (0.25–0.43)
0.16 (0.08–0.24)
0.391
0.003
Obsessive-compulsive behavior
0.28 (0.20–0.36)
0.15 (0.07–0.24)
0.270
0.036
Interpersonal sensitivity
0.27 (0.19–0.35)
0.16 (0.08–0.24)
0.241
0.061
Depression
0.35 (0.27–0.44)
0.16 (0.08–0.24)
0.420
0.001
Anxiety
0.40 (0.29–0.50)
0.12 (0.04–0.21)
0.500
<0.001
Hostility
0.31 (0.21–0.40)
0.15 (0.06–0.24)
0.304
0.019
Phobic anxiety
0.23 (0.14–0.32)
0.13 (0.05–0.21)
0.211
0.101
Paranoid ideation
0.16 (0.08–0.24)
0.12 (0.04–0.21)
0.070
0.586
Psychoticism
0.19 (0.11–0.26)
0.15 (0.08–0.23)
0.077
0.548
Sleep quality
0.76 (0.58–0.94)
0.33 (0.19–0.47)
0.467
<0.001
(1)Statistical analysis was done using intent-to-treat analysis (ITT) with SPSS. (2)Cohen’s d effect size measure, in which an effect size of 0.2 to 0.3 is considered a “small” effect, around 0.5, a “medium” effect, and 0.8 to infinity, a “large” effect, is used here. (3)The P values come from the two sample t-tests.
