Research Article

In Vitro Screening of Medicinal Plants Used in Mexico as Antidiabetics with Glucosidase and Lipase Inhibitory Activities

Table 2

α-glucosidase the 10 most active medicinal plants used in Mexico for diabetes treatment.

Scientific nameLocal nameα-glucosidase % inhibition (0.5 mg mL−1)IC50 (μg mL−1)

Artemisia absinthiumAjenjo45.0 ± 1.7n.d.
Achillea millefoliumMilenrama22.9 ± 1.7n.d.
Calea ternifoliaProdigiosa39.8 ± 2.1n.d.
Camellia sinensis * Te Verde67.3 ± 0.8299
Iostephane heterophyllaZacapal51.4 ± 2.5509
Ludwigia octovalvis Clavillo61.3 ±1.4202
Ricinus communisHiguerilla43.4 ± 2.4n.d.

n.d.: no determined, *reference plant drug control. Percentage of α-glucosidase inhibition was calculated at 10 min as 100% reaction, whereby the reaction = (mean free glucose in sample/mean free glucose in control) × 100.