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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 708452, 11 pages
http://dx.doi.org/10.1155/2012/708452
Research Article

Chinese Herb Astragalus membranaceus Enhances Recovery of Hemorrhagic Stroke: Double-Blind, Placebo-Controlled, Randomized Study

1Department of Neurosurgery, China Medical University Hospital, Taichung 40402, Taiwan
2Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan
3School of Medicine, College of Medicine, China Medical University, Taichung 40402, Taiwan
4Department of Anesthesiology, China Medical University Hospital, Taichung 40402, Taiwan
5Graduate Institute of Biostatistics, College of Public Health, China Medical University, Taichung 40402, Taiwan
6Division of Pediatric Neurology, Department of Pediatrics, China Medical University, Taichung 40402, Taiwan
7Graduate Institute of Acupuncture Science, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan
8Acupuncture Research Center, China Medical University, Taichung 40402, Taiwan
9Department of Chinese Medicine, China Medical University Hospital, Taichung 40402, Taiwan

Received 16 September 2011; Revised 21 December 2011; Accepted 21 December 2011

Academic Editor: Adair Roberto Soares Santos

Copyright © 2012 Chun-Chung Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We tested the effect of Astragalus membranaceus (AM) on acute hemorrhagic stroke. Seventy-eight patients were randomly assigned to Group A (3 g of AM three times/day for 14 days); or Group B (3 g of placebo herb). A total of 68 patients (Group A 36, Group B 32) completed the trial. The increase of functional independence measure scale score between baseline and week 4 was 24.53 ± 23.40, and between baseline and week 12 was 34.69 ± 28.89, in the Group A was greater than 11.97 ± 11.48 and 23.94 ± 14.8 in the Group B (both ). The increase of Glasgow outcome scale score between baseline and week 12 was 0.75 ± 0.77 in the Group A was greater than 0.41 ± 0.50 in the Group B ( ). The results are preliminary and need a larger study to assess the efficacy of AM after stroke.