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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 714512, 7 pages
Review Article

Role of Medicinal Plants and Natural Products on Osteoporotic Fracture Healing

1Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abd Aziz, 50300 Kuala Lumpur, Malaysia
2Department of Basic Medical Science, Kulliyyah of Nursing, International Islamic University Malaysia, Level 2, Jalan Hospital Campus, P.O. Box 141, Pahang Darul Makmur, 25710 Kuantan, Malaysia

Received 13 June 2012; Accepted 17 July 2012

Academic Editor: Ima Nirwana Soelaiman

Copyright © 2012 Mohd Azri Abd Jalil et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Popularly known as “the silent disease” since early symptoms are usually absent, osteoporosis causes progressive bone loss, which renders the bones susceptible to fractures. Bone fracture healing is a complex process consisting of four overlapping phases—hematoma formation, inflammation, repair, and remodeling. The traditional use of natural products in bone fractures means that phytochemicals can be developed as potential therapy for reducing fracture healing period. Located closely near the equator, Malaysia has one of the world’s largest rainforests, which are homes to exotic herbs and medicinal plants. Eurycoma longifolia (Tongkat Ali), Labisia pumila (Kacip Fatimah), and Piper sarmentosum (Kaduk) are some examples of the popular ethnic herbs, which have been used in the Malay traditional medicine. This paper focuses on the use of natural products for treating fracture as a result of osteoporosis and expediting its healing.