Figure 1: Effects of Zuonin B on inhibition of LPS-induced nitric oxide (NO) and prostaglandin E2 (PGE2) production in RAW264.7 cells. Cells cultured in phenol red and serum-free media were pretreated with different concentrations of Zuonin B for 1 h and stimulated with a 1 μg/mL LPS for 24 h. (a) Structure of Zuonin B. (b) NO production. (c) Amount of PGE2 release. (d) Cell viability. NC: untreated control cells; LPS: LPS only treatment. Data represent mean values of three experiments SEM. *Significant difference from NC and #significant difference from LPS, .