Effect of Human Placental Extract on Health Status in Elderly Koreans
Table 2
Change of KoHSME in the two study groups.
Placebo ()
HPE ()
P ‡ value (Placebo versus HPE)‡
Baseline
End
P †
Baseline
End
P †
Physical function
c
3.5 ± 0.7b
0.625
a
3.8 ± 0.5a
0.007
0.036
Daily activity
c
3.9 ± 0.7b
0.420
a
4.1 ± 0.7a
0.983
0.657
Fitness
b
3.6 ± 0.7a
0.316
0.111
0.493
Aging physiological function
3.2 ± 0.8a
3.0 ± 0.8a
0.116
0.001
<0.001
Emotional function
a
3.7 ± 0.6b
0.690
a
0.067
0.440
Depression
a
3.9 ± 0.7b
0.569
a
0.025
0.479
Anxiety
3.4 ± 0.7a
b
0.727
0.364
0.493
Social function
3.6 ± 1.2a
a
0.699
0.881
0.858
Sexual function
a
b
0.230
a
0.020
0.620
General health perception
a
2.5 ± 0.5a
0.254
2.6 ± 0.6a
0.005
0.618
Health status perception
a
a
0.470
0.763
0.477
Health status change
a
a
0.083
0.002
0.218
Functional health satisfaction
a
a
0.717
a
0.004
0.338
Bodily pain
a
b
0.149
b
0.053
0.892
Pain frequency
a
a
0.067
0.043
0.843
Pain intensity
a
b
0.560
b
0.569
0.812
Mean ± SD, a1 data missing, b2 data missing, c: 3 data missing, †change between end and baseline in each group (by Wilcoxon signed ranks test), ‡comparison of mean change between HPE and placebo groups (by Mann-Whitney test), KoHSME; Korean Health Status Measure for the Elderly, and HPE: human placental extract.