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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 734987, 15 pages
Research Article

Explore the Molecular Mechanism of Apoptosis Induced by Tanshinone IIA on Activated Rat Hepatic Stellate Cells

1School of Traditional Chinese Medicine, Chang Gung University, Kweishan, Taoyuan 333, Taiwan
2Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan

Received 23 July 2012; Revised 28 November 2012; Accepted 7 December 2012

Academic Editor: Youn Chul Kim

Copyright © 2012 Tai-Long Pan and Pei-Wen Wang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [8 citations]

The following is the list of published articles that have cited the current article.

  • Tai-Long Pan, Tung-Ho Wu, Pei-Wen Wang, Yann-Lii Leu, Nardnisa Sintupisut, Chun-Hsun Huang, Fang-Rong Chang, and Yang-Chang Wu, “Functional proteomics reveals the protective effects of saffron ethanolic extract on hepatic ischemia-reperfusion injury,” Proteomics, 2013. View at Publisher · View at Google Scholar
  • Tai-Long Pan, Pei-Wen Wang, Yu-Chiang Hung, Chun-Hsun Huang, and Kun-Ming Rau, “Proteomic analysis reveals tanshinone IIA enhances apoptosis of advanced cervix carcinoma CaSki cells through mitochondria intrinsic and endoplasmic reticulum stress pathways,” Proteomics, 2013. View at Publisher · View at Google Scholar
  • Florent Duval, Jorge E. Moreno-Cuevas, Maria Teresa González-Garza, Carlos Rodríguez-Montalvo, and Delia Elva Cruz-Vega, “Liver Fibrosis and Protection Mechanisms Action of Medicinal Plants Targeting Apoptosis of Hepatocytes and Hepatic Stellate Cells,” Advances in Pharmacological Sciences, vol. 2014, pp. 1–11, 2014. View at Publisher · View at Google Scholar
  • Ya-Ting Peng, Ping Chen, Ruo-Yun Ouyang, and Lei Song, “Multifaceted role of prohibitin in cell survival and apoptosis,” Apoptosis, vol. 20, no. 9, pp. 1135–1149, 2015. View at Publisher · View at Google Scholar
  • Ge Wang, Zehao Li, Hao Li, Lidan Li, Jian Li, and Changyuan Yu, “Metabolic Profile Changes of CCl4-Liver Fibrosis and Inhibitory Effects of Jiaqi Ganxian Granule,” Molecules, vol. 21, no. 6, pp. 698, 2016. View at Publisher · View at Google Scholar
  • Xingyu Ze, Jidong Jia, Xinmin Li, Hong You, Xinyan Zhao, Dong Zhang, and Baoen Wang, “Tanshinone IIA promotes the proliferation of WB-F344 hepatic oval cells via Wnt/beta-catenin signaling,” Molecular Medicine Reports, vol. 13, no. 2, pp. 1501–1508, 2016. View at Publisher · View at Google Scholar
  • Ralf Weiskirchen, “Hepatoprotective and Anti-fibrotic Agents: It's Time to Take the Next Step,” Frontiers in Pharmacology, vol. 6, 2016. View at Publisher · View at Google Scholar
  • Yanling Zhao, Xiao Ma, Jiabo Wang, Xuan He, Yaming Zhang, Ye Wang, Honghong Liu, Honghui Shen, and Xiaohe Xiao, “A System Review of Anti-fibrogenesis Effects of Compounds Derived from Chinese Herbal Medicine,” Mini-Reviews In Medicinal Chemistry, vol. 16, no. 2, pp. 163–175, 2016. View at Publisher · View at Google Scholar