Explore the Molecular Mechanism of Apoptosis Induced by Tanshinone IIA on Activated Rat Hepatic Stellate Cells
(a) Histologic examination of rat liver by H&E staining and Masson’s trichrome staining. (b) α-SM-actin expression was presented by immunohistochemical staining. Original magnification: 400x. The intensity of the signals was quantitated by Syngene software and normalized with respect to β-actin used as internal controls. The quantitative results were demonstrated as a bar chart. (c) TUNEL assays for detection of apoptotic cells in liver tissues (400x magnification). The arrows indicated TUNEL-positive signals which were shown in brown color.