Beneficial Effects of Ocimum gratissimum Aqueous Extract on Rats with CCl4-Induced Acute Liver Injury
Figure 8
Proposed model for the inhibitory effects of Ocimum gratissimum aqueous extract and silymarin on the CCl4-induced hepatic stress in rats. Our data demonstrated that Ocimum gratissimum aqueous extract revealed very similar effects on hepatic protection as silymarin by increasing antioxidant activities, reducing of stress-related proteins and MMP9 activity through ERK and NF-κB signaling in livers from CCl4-challenging rats. OGAE indicates Ocimum gratissimum aqueous extract.
