Research Article

Effects of Extract from Solid-State Fermented Cordyceps sinensis on Type 2 Diabetes Mellitus

Figure 2

Effects of Cordyceps sinensis extract on oral glucose tolerance test. After 8 weeks of being fed a high-fat diet, KK/HIJ mice were treated with 300 mg/kg/day of CS extract and 0.5 mg/kg/day of rosiglitazone (RS) for 4 consecutive weeks and were compared to native controls (normal diet) and control group (HFD) after 0 (a), 2 (b), and 4 (c) weeks. After an overnight fast, 3 g/kg D-glucose was administered orally. Blood samples were obtained for evaluation of glucose levels at 0, 15, 45, 95, and 135 min. Nonfasting glucose values (2 hr postprandial hyperglycemia) (d) were also determined 4 weeks later using a glucometer on blood samples. Data are mean ± SE ( for each group); * , as compared to the control group.
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(a)
743107.fig.002b
(b)
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(c)
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(d)