Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Fig 3

Research Article

Effects of Extract from Solid-State Fermented Cordyceps sinensis on Type 2 Diabetes Mellitus

Figure 3

Effect of Cordyceps sinensis extract on insulin tolerance test (ITT). After 8 weeks of being fed a high-fat diet, KK/HIJ mice were treated with 300 mg/kg/day of CS extract and 0.5 mg/kg/day of rosiglitazone (RS) for 4 consecutive weeks and were compared to native controls (normal diet) and control group (HFD) after 0 (a), 2 (b), and 4 (c) weeks. After an overnight fast, 0.5U insulin was administered intraperitoneally. The blood samples were obtained to determine glucose concentrations at 0, 15, 45, 95, and 135 min. Nonfasting serum insulin levels (d) were determined using an insulin ELISA kit 4 weeks later. Data are expressed as mean ± SE ( for each group); * , as compared to the control group.

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