Flavonoid Myricetin Modulates
Receptor Activity through Activation of Channels and CaMK-II Pathway
Myricetin increases the half-decay time of receptor-mediated mIPSCs in PVN neurons. (a) Representative recording of spontaneous receptor-mediated mIPSCs in PVN neurons from a brain slice preparation at a holding potential of −70 mV with voltage-clamp configuration, and in the presence of AP-5, CNQX, and TTX; (b) bar chart shows myricetin increases the half-decay time of the mIPSCs (, paired t-test); (c) diagrams show the effects of myricetin on the decay time, amplitude, and the interevent interval of mIPSCs.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.